胡長龍

發布時間:2021-07-01瀏覽次數:7065

教師基本信息:

姓名:胡長龍

職稱:研究員

電子郵箱:clhu@fudan.edu.cn

辦公地點:万博英超狼队网官方网 C211

辦公電話:021-31246651


研究方向:細胞膜離子通道的功能與調控,以及離子通道異常引起的相關疾病的研究:(1)離子通道對醛固酮以及胰島素的分泌調控;(2)離子通道對神經興奮性及神經損傷修複調控的研究。


個人簡介:

博士,研究員,博士生導師。2005年畢業於万博英超狼队网官方网 ,獲理學博士學位;20057月至200912月,在美國弗吉尼亞大學從事博士後研究;2010-至今,先後任万博英超狼队网官方网 副教授、研究員。主持或參與多項國家自然科學基金麵上項目以及國家重點研發計劃。2007年獲Posdoctoral Fellowship AwardAmerican Heart Association)。2009年獲教育部自然科學二等獎(第3完成人)。


授課情況:生理學;細胞分子生物學;膜片鉗技術和細胞膜離子通道


招生專業:生理學,神經生物學,生物物理學


代表性論文和論著:

1Pan C, Ying Liu, Wang L, Fan W, Ni Y, Zhang X, Wu D, Li C, Li J, Li Z, Liu R, Hu C*. The Kv2.2 channel mediates the inhibition of Prostaglandin E2 on glucose-stimulated insulin secretion in pancreatic β-cells. eLife. 2024 https://doi.org/10.7554/eLife.97234.1.

2.  Wan D, Lu T, Li C, Hu C*. Glucocorticoids rapidly modulate CaV1.2-mediated calcium signals through Kv2.1 channel clusters in hippocampal neurons. J Neurosci. 2024 Sep 19: e0179242024.

3.  Wang Y, Zhang Y, Hu J, Gao Y, Liu Q, Xu W, Xue L, Hu C*.Glucocorticoids modulate neural activity via a rapid non-genomic effect on Kv2.2 channels in the central nervous system.Neurobiology of Stress, 2024, 28:100593.

4.  Li Z.Dong W, Zhang X, Lu J, Mei YA, Hu C*. Protein Kinase C Controls the Excitability of Cortical Pyramidal Neurons by Regulating Kv2.2 Channel Activity. Neurosci Bull, 2022. 38(2): p. 135-148.

5.  Yang T, He M, Zhang H, Barrett PQ, Hu C*. L- and T-type calcium channels control aldosterone production from human adrenals. J Endocrinol, 2020, 244: 237-247.

6He M, Xu Z, Zhang Y, Hu C*. Splice-variant-specific effects of primary aldosteronism point mutations on human Cav3.2 calcium channels. Cell Calcium, 2019, 84: 102104.

7Yang TZhang, Hai-LiangLiang, QingnanShi, YingtangMei, Yan-AiBarrett, Paula QHu C *. Small-Conductance Ca2+-Activated Potassium Channels Negatively Regulate Aldosterone Secretion in Human Adrenocortical Cells. Hypertension, 2016,683):785~7953.  




Name: Changlong Hu

Primary appointment: Professor, Physiology and Neurobiology

Contact Information:

Email:clhu@fudan.edu.cn

Tel: 021-31246651

Address: Room C211, School of life sciences, Fudan University


Education

Ph.D. Neurobiology, Fudan University

PostdocPharmacology, University of Virginia


Research Interests:

Regulation and function of ion channels, and human diseases associated with defects in ion channels. 


Selected Publications:

1Pan C, Ying Liu, Wang L, Fan W, Ni Y, Zhang X, Wu D, Li C, Li J, Li Z, Liu R, Hu C*. The Kv2.2 channel mediates the inhibition of Prostaglandin E2 on glucose-stimulated insulin secretion in pancreatic β-cells. eLife. 2024 https://doi.org/10.7554/eLife.97234.1.

2.  Wan D, Lu T, Li C, Hu C*. Glucocorticoids rapidly modulate CaV1.2-mediated calcium signals through Kv2.1 channel clusters in hippocampal neurons. J Neurosci. 2024 Sep 19: e0179242024.

3.  Wang Y, Zhang Y, Hu J, Gao Y, Liu Q, Xu W, Xue L, Hu C*.Glucocorticoids modulate neural activity via a rapid non-genomic effect on Kv2.2 channels in the central nervous system.Neurobiology of Stress, 2024, 28:100593.

4.  Li Z.Dong W, Zhang X, Lu J, Mei YA, Hu C*. Protein Kinase C Controls the Excitability of Cortical Pyramidal Neurons by Regulating Kv2.2 Channel Activity. Neurosci Bull, 2022. 38(2): p. 135-148.

5.  Yang T, He M, Zhang H, Barrett PQ, Hu C*. L- and T-type calcium channels control aldosterone production from human adrenals. J Endocrinol, 2020, 244: 237-247.

6He M, Xu Z, Zhang Y, Hu C*. Splice-variant-specific effects of primary aldosteronism point mutations on human Cav3.2 calcium channels. Cell Calcium, 2019, 84: 102104.

7Yang TZhang, Hai-LiangLiang, QingnanShi, YingtangMei, Yan-AiBarrett, Paula QHu C *. Small-Conductance Ca2+-Activated Potassium Channels Negatively Regulate Aldosterone Secretion in Human Adrenocortical Cells. Hypertension, 2016,683):785~7953.  


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