姚紅豔

發布時間：2021-06-27瀏覽次數：4652

基本信息

姓名：姚紅豔

職稱：副研究員

電子郵箱：hyao@fudan.edu.cn

辦公地點：複旦生科院D109室

辦公電話：021-31246724

研究方向

發展高通量植物脂質組學技術，結合生物統計、生物化學、細胞生物學、分子遺傳學等學科方法，研究植物環境適應的脂質代謝基礎及分子調控機製；脂質介導的細胞器動態平衡機製。

個人簡介

姚紅豔，女，於1999年、2003年分別獲山東大學學士、碩士學位，2009年獲上海交通大學生物醫學工程（生物技術）專業博士學位。2007-2008年，美國密蘇裏大學、Danforth植物科學中心，訪問學者。2009-2019年，中科院上海植物生理生態研究所（現中科院分子植物卓越創新中心），助理研究員、副研究員。2019年-至今，万博英超狼队网官方网，副研究員。在Nature Communications、PNAS及Plant Cell等上發表SCI論文20餘篇。部分工作被Nature Plants作為“研究亮點”專文評述，Faculty of 1000 所推薦，以及被重要專著《Arabidopsis Book》中“Root Hairs”章節所引用。撰寫相關的綜述論文，發表在重要期刊《Current opinion in Plant Biology》、《Journal of Integrative Plant Biology》、《Journal of Biological Methods》上，並多次被相關領域文章所引用。現任上海植物生物技術學術委員會委員，中國生物物理學會代謝組學分會秘書。

科研項目

1. 國家自然科學基金委員會, 麵上項目, 31870280, 磷脂酰肌醇轉運蛋白（PITP）調控擬南芥葉綠體發育的作用及機製, 2019-01-01至 2022-12-31,結題，主持

2. 國家自然科學基金委員會, 重大研究計劃, 91954206,磷脂分子參與植物細胞器互作及自噬的調控機製, 2020-01-01至 2023-12-31,結題，骨幹

3. 國家重點研發計劃，2016YFD0100902-09，水稻品質性狀的分子調控網絡分析，2016-7-1至2020-12-31，65萬，結題，骨幹

4.國家自然科學基金委員會, 青年項目, 31400261, β-酮酰-ACP合酶I及脂肪酸調控植物根毛發生的分子機製研究, 2015-01-01 至 2017-12-31, 結題，主持

5. 國家自然科學基金國際(地區)合作與交流項目（NSFC-NWO 項目），31110236，環境信號調控植物根係發育的機理研究，2012-01-01至2015-12-31，結題，參與

6. 中國科學院上海生命科學研究院優秀青年人才領域前沿項目，No.2011KIP304，磷脂酸調控植物細胞囊泡運輸和生長素運輸機製的研究，2011-06-01至2013-06-30，結題，主持

授課情況

主要承擔專業必修課《生物化學》的教學工作，參與“思政討論課”、“生命科學交叉前沿專題”課程的教學工作。

招生專業

生物化學與分子生物學、生物與醫藥

代表性論文

1. Lyu MA^#, Du H^#, Yao H^#, Zhang Z^#, Chen G, Huang Y, Ni X, Chen F, Zhao YY, Tang Q, Miao F, Wang Y, Zhao Y, Lu H, Fang L, Gao Q, Qi Y, Zhang Q, Zhang J, Yang T, Cui X, Liang C, Lu T and Zhu XG. A dominant role of transcriptional regulation during the evolution of C4 photosynthesis in Flaveria species. Nat Commun*. 2025, 16:1643.

2. Qian W, Tang H and Yao H. Lipidomics and temporal-spatial distribution of organelle lipid. J. Biol. Methods.* 2025, 12: e99010049.

3. Yao H^#, Lu Y^#, Yang X^#, Wang X, Luo Z, Lin D, Wu J* and Xue H. Arabidopsis Sec14 proteins (SFH5 and SFH7) mediate inter-organelle transport of phosphatidic acid and regulate chloroplast development. Proc. Natl. Acad. Sci. U S A2023, 120: e2221637120. (research highlights in Nature Plants*)

4. Qian W, Zhu Y, Chen Q, Wang S, Chen L, Liu T, Tang H* and YaoH. Comprehensive metabolomic and lipidomic alterations in response to heat stress during seed germination and seedling growth of Arabidopsis. Front. Plant Sci.*2023, 14.

5. Du X, Yao H, Luo P, Tang X, Xue H. Cytidinediphosphate diacylglycerol synthase-Mediated phosphatidic acid metabolism is crucial for early embryonic development of Arabidopsis. PLoS Genet.* 2022, 18: e1010320.

6. Lin D^#, Yao H^#, Jia L, Tan J, Xu Z, Zheng W* and Xue H. Phospholipase D-derived phosphatidic acid promotes root hair development under phosphorus deficiency by suppressing vacuolar degradation of PIN2. New Phytol.* 2020, 226: 142–155.

7. Chen C, He B, Liu X, Ma X, Liu Y, Yao H, Zhang P, Yin J, Wei X, Koh HJ, Yang C, Xue HW, Fang Z, Qiao Y. Pyrophosphate-fructose 6-phosphate 1-phosphotransferase (PFP1) regulates starch biosynthesis and seed development via heterotetramer formation in rice (Oryza sativa L.). Plant Biotechnol J. 2020, 18: 83-95.

8. Yao H and Xue H. Phosphatidic acid (PA) plays key roles regulating plant development and stress responses. J. Integr. Plant Biol.* 2018, 60: 851-863.

9. Wang Y, Yao H* and Xue H. Lipidomic profiling analysis reveals the dynamics of phospholipid molecules in Arabidopsis thaliana seedling growth. J. Integr. Plant Biol. 2016, 58:890-902. (Cover*).

10. Deng T^#, Yao Y^#, Wang J^#, Wang J, Xue H* and Zuo K*. GhLTPG1, a cotton GPI-anchored lipid transfer protein, regulates the transport of phosphatidylinositol monophosphates and cotton fiber elongation. Sci. Rep.2016, 6:26829.

11. Gao Q^#, Lu Y^#, Yao H^#, Xu Y, Huang W and Wang C. Phospholipid homeostasis maintains cell polarity, development and virulence in metarhizium robertsii. Environ. Microbiol.* 2016, 18:3976-3990.

12. Yu F^#, He F^#, Yao H, Wang C, Wang J, Li J, Qi X, Xue H, Ding J and Zhang P. Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex. EMBO Rep.2015, 16:813-823. (recommended by F1000 Prime*).

13. Yao H, Wang G and Wang X. Nuclear translocation of proteins and the effect of phosphatidic acid. Plant Signal. & Behav*. 2014, 9:12, e977711.

14. Yao H^#, Wang G^#, Guo G and Wang X. Phosphatidic acid interacts with a MYB transcription factor and regulates its nuclear localization and function in Arabidopsis. Plant Cell2013, 25: 5030-5042. (recommended by F1000 Prime*).

15. Yao H and Xue H. Signals and mechanisms affecting vesicular trafficking during root growth. Curr. Opin. Plant Biol.*2011,14: 571-579.

16. Yao H^#, Zhang T^#, Xue H, Tang K* and Li R. Biomimetic affinity purification of Candida antarctica* lipase B. J. Chromatogr. B2011, 879: 3896-3900.

姚紅豔

2. Qian W, Tang H and Yao H*. Lipidomics and temporal-spatial distribution of organelle lipid. J. Biol. Methods. 2025, 12: e99010049.

3. Yao H#, Lu Y#, Yang X#, Wang X, Luo Z, Lin D, Wu J* and Xue H*. Arabidopsis Sec14 proteins (SFH5 and SFH7) mediate inter-organelle transport of phosphatidic acid and regulate chloroplast development. Proc. Natl. Acad. Sci. U S A2023, 120: e2221637120. (research highlights in Nature Plants)

4. Qian W, Zhu Y, Chen Q, Wang S, Chen L, Liu T, Tang H* and YaoH*. Comprehensive metabolomic and lipidomic alterations in response to heat stress during seed germination and seedling growth of Arabidopsis. Front. Plant Sci.2023, 14.

5. Du X, Yao H, Luo P, Tang X, Xue H*. Cytidinediphosphate diacylglycerol synthase-Mediated phosphatidic acid metabolism is crucial for early embryonic development of Arabidopsis. PLoS Genet. 2022, 18: e1010320.

6. Lin D#, Yao H#, Jia L, Tan J, Xu Z, Zheng W* and Xue H*. Phospholipase D-derived phosphatidic acid promotes root hair development under phosphorus deficiency by suppressing vacuolar degradation of PIN2. New Phytol. 2020, 226: 142–155.

8. Yao H and Xue H*. Phosphatidic acid (PA) plays key roles regulating plant development and stress responses. J. Integr. Plant Biol. 2018, 60: 851-863.

9. Wang Y, Yao H* and Xue H*. Lipidomic profiling analysis reveals the dynamics of phospholipid molecules in Arabidopsis thaliana seedling growth. J. Integr. Plant Biol. 2016, 58:890-902. (Cover).

10. Deng T#, Yao Y#, Wang J#, Wang J, Xue H* and Zuo K*. GhLTPG1, a cotton GPI-anchored lipid transfer protein, regulates the transport of phosphatidylinositol monophosphates and cotton fiber elongation. Sci. Rep.2016, 6:26829.

11. Gao Q#, Lu Y#, Yao H#, Xu Y, Huang W and Wang C*. Phospholipid homeostasis maintains cell polarity, development and virulence in metarhizium robertsii. Environ. Microbiol. 2016, 18:3976-3990.

12. Yu F#, He F#, Yao H, Wang C, Wang J, Li J, Qi X, Xue H*, Ding J* and Zhang P*. Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex. EMBO Rep.2015, 16:813-823. (recommended by F1000 Prime).

13. Yao H*, Wang G and Wang X. Nuclear translocation of proteins and the effect of phosphatidic acid. Plant Signal. & Behav. 2014, 9:12, e977711.

14. Yao H#, Wang G#, Guo G and Wang X*. Phosphatidic acid interacts with a MYB transcription factor and regulates its nuclear localization and function in Arabidopsis. Plant Cell2013, 25: 5030-5042. (recommended by F1000 Prime).

15. Yao H and Xue H*. Signals and mechanisms affecting vesicular trafficking during root growth. Curr. Opin. Plant Biol.2011,14: 571-579.

16. Yao H#, Zhang T#, Xue H, Tang K* and Li R*. Biomimetic affinity purification of Candida antarctica lipase B. J. Chromatogr. B2011, 879: 3896-3900.