教師基本信息：
姓名：馮會娟
職稱：青年研究員
職務：研究組長（PI）
電子郵箱：huijuanfeng@fudan.edu.cn
辦公地點：万博英超狼队网官方网 A113
辦公電話：
個人網頁/課題組主頁：https://huijfeng.github.io
個人簡介：
2011年獲華中科技大學生物信息技術專業學士學位，2016年獲清華大學生物信息學專業博士學位，2016年至2021年在美國哥倫比亞大學係統生物學係從事博士後研究，2022年加入万博英超狼队网官方网 ，任青年研究員，博士生導師。
研究方向：
融合生物信息學方法開發和高通量多組學數據建模，分析和挖掘，聚焦疾病和發育中可變剪接的功能和調控機製，並針對剪接相關疾病，探索其RNA治療方法。
本實驗室長期歡迎對以上方向感興趣的本科生和研究生加入我們開展科學研究。感興趣的同學可通過郵件聯係（huijuanfeng@fudan.edu.cn）並附上簡曆。
招生專業
生物信息學、計算生物學
代表性論文和論著：
*共同第一作者
1. Feng H, Moakley DF, Chen S, McKenzie MG, Menon V, Zhang C. Complexity and graded regulation of neuronal cell type-specific alternative splicing revealed by single-cell RNA sequencing. PNAS, 2021; 118(10).
2. Feng H*, Bao S*, Weyn-Vanhentenryck SM, Khan A, Wong J, Shah A, Flynn ED, Zhang C. Modeling the in vivo specificity of RNA-binding proteins by precisely registering protein-RNA crosslink sites. Molecular Cell. 2019;74 (6), 1189-1204. e6.
3. Weyn-Vanhentenryck SM*, Feng H*, Ustianenko D, Duffie R, Yan Q, Jacko M, Martinez JC, Goodwin M, Zhang X, Hengst U, Lomvardas S, Swanson MS, Zhang C. Precise temporal regulation of alternative splicing during neural development. Nature Communications. 2018;9(1):2189.
4. Feng H, Li T, Zhang X. Characterization of kinase gene expression and splicing profile in prostate cancer with RNA-Seq data. BMC Genomics. 2018;19(6):153.
5. Feng H, Zhang X, Zhang C. mRIN for direct assessment of genome-wide and gene-specific mRNA integrity from large-scale RNA-sequencing data. Nature Communications. 2015;6:7816.
6. Feng H, Qin Z, Zhang X. Opportunities and methods for studying alternative splicing in cancer with RNA-Seq. Cancer Letters. 2013;340(2):179-91.
7. Jacko M, Weyn-Vanhentenryck SM, Smerdon JW, Yan R, Feng H, Williams DJ, Pai J, Xu K, Wichterle H, Zhang C. Rbfox Splicing Factors Promote Neuronal Maturation and Axon Initial Segment Assembly. Neuron. 2018;97(4):853-68 e6.
8. Genestine M, Ambriz D, Crabtree GW, Dummer P, Molotkova A, Quintero M, Mela A, Biswas S, Feng H, Zhang C, Canoll P, Hargus G, Agalliu D, Gogos JA, Au E. Vascular-derived SPARC and SerpinE1 regulate interneuron tangential migration and accelerate functional maturation of human stem cell-derived interneurons. Elife. 2021; 10, e56063.
9. Oku S, Feng H, Connor S, Toledo A, Zhang P, Zhang Y, Thoumine O, Zhang C, Craig AM. Alternative splicing at neuroligin site A regulates glycan interaction and synaptogenic activity. Elife. 2020; 9, e58668.