職稱：教授
電話：02151630503
地址：狗万外围充值 江灣校區生命科學院
個人簡介
1963年11月出生，女，狗万外围充值 特聘教授。
1991.9-1996.7，美國哥倫比亞大學，遺傳學博士
1996-1997，法國國際癌症研究機構 博士後
1997-1998，美國匹茲堡大學 助理教授 (研究係列)
1998-2004，美國約翰·霍普金斯·布隆伯格公共衛生學院 助理教授
2004-2007，美國約翰·霍普金斯·布隆伯格公共衛生學院 副教授 (終身)
2007-2016，美國國家精神衛生研究所遺傳流行病學研究組負責人
2016-今，美國國家精神衛生研究所統計基因組學和數據分析中心主任
2017-今，狗万外围充值 生命科學院特聘教授
研究方向
長期從事統計遺傳學、精神病遺傳學和計算生物學的研究
主要獲獎及榮譽
2001年：約翰霍普金斯大學醫學院“NIH Directors award”
2003年： 約翰霍普金斯大學公共衛生學院“The Louis I. and Thomas D. Dublin award”
2006年：約翰霍普金斯大學公共衛生學院 “The Helen Abbey Award for Advising, Mentoring and Teaching Recognition”
學術任職
2001年：美國人類遺傳學會
2010年：國際遺傳流行病學學會
2012年：國際精神病學遺傳學大會
2007年：HUGO泛亞SNP數據庫委員會
2016年：“World journal of psychiatry”編委
國際學術會議
1) UICC anti-cancer congress (1999), Japan
2) UICC Familial Cancer Project and International Oncology Conference (2001), China
3) Genetic Society of Hodgkin's Lymphoma (2001), German
4) Genomic Medicine (2011), China
5) Nature Conference: Genomic Analysis of Diseases (2012), China
6) International society of psychiatric genetics (2014), Denmark
7) International society of human genetics (2016), Japan
8）Biological Psychiatry Annual Conference, (2018), USA
撰寫書籍
《Applied Computational Genomics》
代表性成果
(#並列一作，*通訊)
1. Bing-Jian, F., Huang, W., Shugart, Y.Y. #, et al.2002. Genome-wide scan for familial nasopharyngeal carcinoma reveals evidence of linkage to chromosome 4.;Nature genetics,;31(4), p.395.
2. Shugart, Y.Y. #, et al, 2006. Genomewide linkage scan for obsessive-compulsive disorder: evidence for susceptibility loci on chromosomes 3q, 7p, 1q, 15q, and 6q.;Molecular psychiatry,;11(8), p.763.
3. Qin H, et al, Nestadt G, Shugart, Y.Y.*, 2016. Whole genome association analysis of treatment response in obsessive-compulsive disorder.;Molecular psychiatry,;21(2), p.270.
4. Qin, H.D., Shugart, Y.Y. #, et al. and Zeng, Y.X., 2011. Comprehensive pathway-based association study of DNA repair gene variants and the risk of nasopharyngeal carcinoma.;Cancer research, pp.canres-0469.
5. Shugart, Y.Y. #, 1998. Anticipation in familial Hodgkin lymphoma.;American journal of human genetics,;63(1), p.270.
6. Qin, H.D., et al, Shugart, Y.Y.*, Jia WH*. 2016. Genomic characterization of esophageal squamous cell carcinoma reveals critical genes underlying tumorigenesis and poor prognosis.;The American Journal of Human Genetics,;98(4), pp.709-727.
7. Xu, Y., Yue, W., Shugart, Y.Y. #, et al., 2015. Exploring transcription factors-microRNAs Co-regulation networks in schizophrenia.;Schizophrenia bulletin,;42(4), pp.1037-1045.
8. Ritter, M.L., et al, Gerald Nestadt* and Shugart, Y.Y.* 2017. Genome Wide Association Study (GWAS) between Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD).;Frontiers in molecular neuroscience,;10.
9. Hong, S.E., Shugart, Y.Y., et al. and Walsh, C.A., 2000. Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations.;Nature genetics,;26(1), p.93.
10. Willour, V.L., Shugart, Y.Y., et al., 2004. Replication study supports evidence for linkage to 9p24 in obsessive-compulsive disorder.;The American Journal of Human Genetics,;75(3), pp.508-513.
11. Ahn, K., An, S.S., Shugart, Y.Y. and Rapoport, J.L., 2016. Common polygenic variation and risk for childhood-onset schizophrenia.;Molecular psychiatry,;21(1), p.94.
12. Cao, H., Duan, J., Lin, D., Shugart, Y.Y., Calhoun, V. and Wang, Y.P., 2014. Sparse representation based biomarker selection for schizophrenia with integrated analysis of fMRI and SNPs.;Neuroimage,;102, pp.220-228.
13. Kiezun, A., Garimella, K., Do, R., Stitziel, N.O., Neale, B.M., McLaren, P.J., Gupta, N., Sklar, P., Sullivan, P.F., Moran, J.L. and Hultman, C.M., 2012. Exome sequencing and the genetic basis of complex traits.;Nature genetics,;44(6), pp.623-630.