姓名：董愛武
職稱：教授
職務：
辦公地點：淞滬路2005號，狗万外围充值 江灣校區，万博体育分 A401，上海，200438
辦公電話：021-31246633
研究方向
植物表觀遺傳學
利用生物化學、遺傳學、結構生物學、生物信息學等方法研究植物生長發育和環境適應過程中的表觀遺傳調控機製。主要包括(1)染色質組裝與重塑調控植物細胞命運和生長發育的分子機製，(2)組蛋白甲基化修飾及其識別調節植物生長發育及環境適應的分子機製。
個人簡介
1989-1993，吉林大學，獲得生物化學學士學位；1993-1996，北京大學，獲得生物化學碩士學位；2000-2003，狗万外围充值 ，獲得生物化學博士學位。1996年起，万博英超狼队网官方网 任教，曆任助教、講師、副教授、教授，現任狗万外围充值 生物化學係主任。工作以來，主持多項國家自然科學基金麵上、重點、重大研究計劃等科研項目。2013年起擔任法國國家科學研究中心植物表觀遺傳學國際聯合實驗室中方主任。曾獲教育部優秀青年教師（2003年）、上海市科技啟明星（2003年）、上海市曙光學者（2008年）等稱號，2007年獲得中國青年女科學家獎。
授課情況
生物化學-榮譽課程，表觀遺傳學-榮譽課程
招生專業
生物化學(表觀遺傳方向)
代表性論文和論著(*通訊作者)
1. Chen K, Du K, Shi Y, Yin L, Shen WH, Yu Y, Liu B*, Dong A*. (2021) H3K36 methyltransferase SDG708 enhances drought tolerance by promoting abscisic acid biosynthesis in rice. New Phytol. doi: 10.1111/nph.17290
2. Luo Q, Wang B, Wu Z, Jiang W, Wang Y, Du K, Zhou N, Zheng L, Gan J, Shen WH, Ma J*, Dong A*. (2020) NAP1-Related Protein 1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B. Proc Natl Acad Sci U S A. 117(48):30391-30399. doi: 10.1073/pnas.2011089117
3. Du K, Luo Q, Yin L, Wu J, Liu Y, Gan J, Dong A*, Shen WH*. (2020) OsChz1 acts as a histone chaperone in modulating chromatin organization and genome function in rice. Nat Commun. 11(1):5717. doi: 10.1038/s41467-020-19586-z
4. An Z, Yin L, Liu Y, Peng M, Shen WH*, Dong A*. (2020) The histone methylation readers MRG1/MRG2 and the histone chaperones NRP1/NRP2 associate in fine-tuning Arabidopsis flowering time. Plant J. 103(3):1010-1024. doi: 10.1111/tpj.14780
5. Wang B, Luo Q, Li Y, Yin L, Zhou N, Li X, Gan J*, Dong A*. (2020) Structural insights into target DNA recognition by R2R3-MYB transcription factors. Nucleic Acids Res. 48(1):460-471. doi: 10.1093/nar/gkz1081
6. Liu B, Liu Y, Wang B, Luo Q, Shi J, Gan J, Shen W-H, Yu Y*, Dong A*. (2019) The transcription factor OsSUF4 interacts with SDG725 in promoting H3K36me3 establishment. Nat Commun. 10(1):2999. doi: 10.1038/s41467-019-10850-5
7. Liu Y, Liu K, Yin L, Yu Y, Qi J, Shen WH, Zhu J, Zhang Y*, Dong A*. (2019) H3K4me2 functions as a repressive epigenetic mark in plants. Epigenetics Chromatin. 12(1):40. doi: 10.1186/s13072-019-0285-6
8. Jiang W, Li Z, Yao X, Zheng B, Shen WH, Dong A*. (2018) jaw-1D: a gain-of-function mutation responsive to paramutation-like induction of epigenetic silencing. J Exp Bot. 70(2):459-468. doi: 10.1093/jxb/ery365
9. Wei G, Liu K, Shen T, Shi J, Liu B, Han M, Peng M, Fu H, Song Y, Zhu J*, Dong A*, Ni T*. (2018) Position-specific intron retention is mediated by the histone methyltransferase SDG725. BMC Biol. 16(1):44. doi: 10.1186/s12915-018-0513-8
10. Li C, Liu Y, Shen WH, Yu Y*, Dong A*. (2018) Chromatin-remodeling factor OsINO80 is involved in regulation of gibberellin biosynthesis and is crucial for rice plant growth and development. J Integr Plant Biol. 60(2):144-159. doi: 10.1111/jipb.12603
11. Liu K, Yu Y, Dong A*, Shen WH*. (2017) SET DOMAIN GROUP701 encodes a H3K4-methytransferase and regulates multiple key processes of rice plant development. New Phytol. 215(2):609-623. doi: 10.1111/nph.14596
12. Zhu Y*, Rong L, Luo Q, Wang B, Zhou N, Yang Y, Zhang C, Feng H, Zheng L, Shen WH, Ma J*, Dong A*. (2017) The Histone Chaperone NRP1 Interacts With WEREWOLF to Activate GLABRA2 in Arabidopsis Root Hair Development. Plant Cell. 29(2):260-276. doi: 10.1105/tpc.16.00719
13. Zhou W, Gao J, Ma J, Cao L, Zhang C, Zhu Y, Dong A*, Shen WH*. (2016) Distinct roles of the histone chaperones NAP1 and NRP and the chromatin-remodeling factor INO80 in somatic homologous recombination in Arabidopsis thaliana. Plant J. 88(3):397-410. doi: 10.1111/tpj.13256
14. Liu B, Wei G, Shi J, Jin J, Shen T, Ni T, Shen WH, Yu Y*, Dong A*. (2016) SET DOMAIN GROUP 708, a histone H3 lysine 36-specific methyltransferase, controls flowering time in rice. New Phytol. 210(2):577-88. doi: 10.1111/nph.13768
15. Jin J, Shi J, Liu B, Liu Y, Huang Y, Yu Y*, Dong A*. (2015) MRG702, a reader protein of H3K4me3 and H3K36me3, is involved in brassinosteroid-regulated growth and flowering time control in rice. Plant Physiol. 168(4):1275-85. doi: 10.1104/pp.114.255737
16. Zhang C, Cao L, Rong L, An Z, Zhou W, Ma J, Shen WH, Zhu Y*, Dong A*. (2015) The chromatin-remodeling factor AtINO80 plays crucial roles in genome stability maintenance and in plant development. Plant J. 82(4):655-68. doi: 10.1111/tpj.12840
17. Bu Z, Yu Y, Li Z, Liu Y, Jiang W, Huang Y, Dong A*. (2014) Regulation of Arabidopsis flowering by the histone mark readers MRG1/2 via interaction with CONSTANS to modulate FT expression. PLoS Genet. 10(9):e1004617. doi: 10.1371/journal.pgen.1004617
18. Weng M, Yang Y, Feng H, Pan Z, Shen WH, Zhu Y*, Dong A*. (2014) Histone chaperone ASF1 is involved in gene transcription activation in response to heat stress in Arabidopsis thaliana. Plant Cell Environ. 37(9):2128-38. doi: 10.1111/pce.12299
19. Sui P, Shi J, Gao X, Shen WH, Dong A*. (2013) H3K36 methylation is involved in promoting rice flowering.Mol Plant. 6(3):975-7. doi: 10.1093/mp/sss152
20. Li Z, Li B, Shen WH, Huang H, Dong A*. (2012) TCP transcription factors interact with AS2 in the repression of class-I KNOX genes in Arabidopsis thaliana.Plant J. 71(1):99-107. doi: 10.1111/j.1365-313X.2012.04973.x
21. Sui P, Jin J, Ye S, Mu C, Gao J, Feng H, Shen WH, Yu Y*, Dong A*. (2012) H3K36 methylation is critical for brassinosteroid-regulated plant growth and development in rice.Plant J. 70(2):340-7. doi: 10.1111/j.1365-313X.2011.04873.x
22. Li Z, Li B, Dong A*. (2012) The Arabidopsis transcription factor AtTCP15 regulates endoreduplication by modulating expression of key cell-cycle genes.Mol Plant. 5(1):270-80. doi: 10.1093/mp/ssr086
23. Zhu Y, Weng M, Yang Y, Zhang C, Li Z, Shen WH*, Dong A*. (2011) Arabidopsis homologues of the histone chaperone ASF1 are crucial for chromatin replication and cell proliferation in plant development.Plant J. 66(3):443-55. doi: 10.1111/j.1365-313X.2011.04504.x
24. Liu Z, Gao J, Dong A*, Shen WH*. (2009) A truncated Arabidopsis NUCLEOSOME ASSEMBLY PROTEIN 1, AtNAP1;3T, alters plant growth responses to abscisic acid and salt in the Atnap1;3-2 mutant.Mol Plant. 2(4):688-99. doi: 10.1093/mp/ssp026
25. Liu Z, Zhu Y, Gao J, Yu F, Dong A*, Shen WH*. (2009) Molecular and reverse genetic characterization of NUCLEOSOME ASSEMBLY PROTEIN1 (NAP1) genes unravels their function in transcription and nucleotide excision repair in Arabidopsis thaliana.Plant J. 59(1):27-38. doi: 10.1111/j.1365-313X.2009.03844.x
26. Zhu Y, Dong A*, Meyer D, Pichon O, Renou JP, Cao K, Shen WH*. (2006) Arabidopsis NRP1 and NRP2 encode histone chaperones and are required for maintaining postembryonic root growth.Plant Cell. 18(11):2879-92
27. Yang L, Liu Z, Lu F, Dong A*, Huang H*. (2006) SERRATE is a novel nuclear regulator in primary microRNA processing in Arabidopsis.Plant J. 47(6):841-50
28. Dong A*, Liu Z, Zhu Y, Yu F, Li Z, Cao K, Shen WH. (2005) Interacting proteins and differences in nuclear transport reveal specific functions for the NAP1 family proteins in plants.Plant Physiol. 138(3):1446-56