姓名：葛曉春
職稱：教授
職務：教師
電子郵箱：xcge@fudan.edu.cn
辦公地點：生科院樓D417
辦公電話：021-31246642
個人網頁/課題組主頁：
研究方向
植物分子生物學、逆境生物學
個人簡介
狗万外围充值 本科、碩士及博士學位，2003-2005年美國Donald Danforth Plant Science Center 博士後，2003年起先後任狗万外围充值 生物化學係副教授及教授職位。已獲得7項 國家自然科學基金項目、2項上海市科委重點項目和1項上海市人才計劃項目的資助；作為項目核心成員參與兩項國家重大轉基因專項“重要性狀基因克隆及功能驗證”以及“水稻節水穩產新基因及啟動子的克隆與功能驗證”以及1項國家973項目“作物水分高效利用機理與調控的基礎研究”；2006年入選上海市浦江人才計劃。在 Current Biology, Molecular Plant, Plant Cell, Plant Journal, Plant Physiology, EMBO Reports，Plant Molecular Biology等雜誌上發表通訊或者第一作者論文多篇，申請專利10項，有7項已獲得授權；做為主編出版譯著《蛋白質結構與功能》，並參與植物分子生物學專業重要教材《植物生理學》的翻譯及編輯工作。
研究興趣
全世界範圍內，由於環境脅迫因素引起的作物產量損失不計其數。實驗室主要致力於揭示植物應對環境因素變化的機製，以及利用已擁有專利的基因來提高作物抗非生物逆境及抗除草劑的能力。實驗室的主要研究方向為：1)植物抗逆境相關基因的功能研究，包括抗旱、抗除草劑等基因的功能研究;2)細胞死亡調控相關基因在植物逆境響應信號途徑中的功能。
授課情況
主講本科生課程《核酸的化學與生物學》；研究生課程《核酸化學》
招生專業
植物分子生物學，生物化學，生物工程
代表性論文和論著
1.Lv Z, Zhao M, Wang W, Huang M, Li C, Lian Q, Xia J, Qi J, Xiang C, Tang H, Ge X*. (2021) Changing Gly311 to acidic amino acid in the MATE family protein DTX6 leads to enhanced resistance of Arabidopsis to the dihydropyridine herbicides. Mol. Plant, 14: 1-11
2.Gu Z, Pan W, Chen W, Ge X*. (2019) New perspectives on the plant PARP family: Arabidopsis PARP3 is inactive, and PARP1 exhibits predominant poly (ADP-ribose) polymerase activity in response to DNA damage. BMC plant Biol., 19: 364
3.Yao L, Cheng X, Gu Z, Huang W, Li S, Wang L, Wang Y, Xu P, Ma H, Ge X*. (2018) AWPM-19 family protein OsPM1 mediates abscisic acid influx and drought response in rice. Plant Cell, 30: 1258-1276
4.Jin Y, Pan W, Zheng X, Cheng X, Liu M, Ma H*, Ge X*. (2018) OsERF101, an ERF family transcription factor, regulates drought stress response in reproductive tissues. Plant Mol. Biol., 98:51-65
5.Liu C, Wu Q, Liu W, Gu Z, Wang W, Xu P, Ma H, Ge X*. (2017) Poly(ADP-ribose) polymerases regulate root cell division and inhibition of PARP activities enhances root development. J. Integr. Plant Biol., 59(7): 459-474
6.Guo C, Yao L, You C, Wang S, Cui J, Ge X*, Ma H*. (2016) MID1 plays an important role in response to drought stress during reproductive development. Plant J., 88(2): 280-293.
7.Zhang H, Gu Z, Wu Q, Yang L, Liu C, Ma H, Xia Y, Ge X*. (2015) Arabidopsis PARG1 is the key factor promoting cell survival among the enzymes regulating post-translational poly(ADP-ribosyl)ation. Sci. Rep., 5:15892. doi: 10.1038/srep15892. .
8.Jin Y, Yang H, Wei Z, Ma H, Ge X*. (2013) Rice male development under drought stress: phenotypic changes and stage-dependent transcriptomic reprogramming. Mol. Plant, 6: 1630-45.
9.Wang H, Lu Y, Liu P, Wen W, Zhang J, Ge X*, Xia Y*. (2013) The ammonium/ nitrate ratio is an input signal in the temperature-modulated, SNC1-mediated and EDS1-dependent autoimmunity of nudt6-2nudt7. Plant J., 73: 262-275.
10. Ge X, Chang F, Ma H. (2010) Signaling and transcriptional control of reproductive development in Arabidopsis. Curr. Biol., 20: 988-997
11. Ge X, Li G, Wang S, Zhu H, Zhu T, Wang X, Xia Y*. (2007) AtNUDT7, a negative regulator of basal immunity in arabidopsis, modulates two distinct defense response pathways and is involved in maintaining redox homeostasis. Plant Physiol., 145: 204-215
12. Ge X, Dietrich C, Matsuno M, Li G, Berg H, Xia Y*. (2005) An Arabidopsis aspartic protease functions as an anti-cell-death component in reproduction and embryogenesis. EMBO Rep., 6(3):283-288.
Selected Publications：
1.Lv Z, Zhao M, Wang W, Huang M, Li C, Lian Q, Xia J, Qi J, Xiang C, Tang H, Ge X*. (2021) Changing Gly311 to acidic amino acid in the MATE family protein DTX6 leads to enhanced resistance of Arabidopsis to the dihydropyridine herbicides. Mol. Plant, 14: 1-11
2.Gu Z, Pan W, Chen W, Ge X*. (2019) New perspectives on the plant PARP family: Arabidopsis PARP3 is inactive, and PARP1 exhibits predominant poly (ADP-ribose) polymerase activity in response to DNA damage. BMC plant Biol., 19: 364
3.Yao L, Cheng X, Gu Z, Huang W, Li S, Wang L, Wang Y, Xu P, Ma H, Ge X*. (2018) AWPM-19 family protein OsPM1 mediates abscisic acid influx and drought response in rice. Plant Cell, 30: 1258-1276
4.Jin Y, Pan W, Zheng X, Cheng X, Liu M, Ma H*, Ge X*. (2018) OsERF101, an ERF family transcription factor, regulates drought stress response in reproductive tissues. Plant Mol. Biol., 98:51-65
5.Liu C, Wu Q, Liu W, Gu Z, Wang W, Xu P, Ma H, Ge X*. (2017) Poly(ADP-ribose) polymerases regulate root cell division and inhibition of PARP activities enhances root development. J. Integr. Plant Biol., 59(7): 459-474
6.Guo C, Yao L, You C, Wang S, Cui J, Ge X*, Ma H*. (2016) MID1 plays an important role in response to drought stress during reproductive development. Plant J., 88(2): 280-293.
7.Zhang H, Gu Z, Wu Q, Yang L, Liu C, Ma H, Xia Y, Ge X*. (2015) Arabidopsis PARG1 is the key factor promoting cell survival among the enzymes regulating post-translational poly(ADP-ribosyl)ation. Sci. Rep., 5:15892. doi: 10.1038/srep15892. .
8.Jin Y, Yang H, Wei Z, Ma H, Ge X*. (2013) Rice male development under drought stress: phenotypic changes and stage-dependent transcriptomic reprogramming. Mol. Plant, 6: 1630-45.
9.Wang H, Lu Y, Liu P, Wen W, Zhang J, Ge X*, Xia Y*. (2013) The ammonium/ nitrate ratio is an input signal in the temperature-modulated, SNC1-mediated and EDS1-dependent autoimmunity of nudt6-2nudt7. Plant J., 73: 262-275.
10. Ge X, Chang F, Ma H. (2010) Signaling and transcriptional control of reproductive development in Arabidopsis. Curr. Biol., 20: 988-997
11. Ge X, Li G, Wang S, Zhu H, Zhu T, Wang X, Xia Y*. (2007) AtNUDT7, a negative regulator of basal immunity in arabidopsis, modulates two distinct defense response pathways and is involved in maintaining redox homeostasis. Plant Physiol., 145: 204-215
12. Ge X, Dietrich C, Matsuno M, Li G, Berg H, Xia Y*. (2005) An Arabidopsis aspartic protease functions as an anti-cell-death component in reproduction and embryogenesis. EMBO Rep., 6(3):283-288.