教師基本信息：
姓名：張智
職稱：副高級
職務：青年副研究員
電子郵箱：z_zhang@fudan.edu.cn
辦公地點：狗万外围充值 江灣校區生科樓C117
辦公電話：021-31246768
研究方向：
課題組主要研究中樞對能量代謝的神經調控，尤其專注於雌激素在下丘腦對體溫、飲食和能量代謝的調節機製研究。以基因編輯的實驗動物為模型，綜合利用光、化學遺傳學，神經鈣成像，單細胞測序和行為學等方法，揭示大腦調節能量穩態的神經原理和對肥胖等代謝疾病的致病機理。
Research Interests:
We are interested in understanding the central role of the peripheral hormones, e.g. estrogens， in the regulation of body temperature, energy intake and energy expenditure.These studies can help us better understand how the brain controls our body weight and maintains our metabolic health.
個人簡介：
張智，万博英超狼队网官方网 青年副研究員。荷蘭阿姆斯特丹大學博士，美國加州大學洛杉磯分校（UCLA）博士後。在Nature Communications, Nature metabolism, eLife 等雜誌發表 SCI論文19篇。曾獲美國女性健康研究會青年科學家獎、美國心髒協會博士後獎、UCLA博士後校長獎提名等獎勵。現主持國家自然科學基金項目1項，任中國生物物理協會會員，Frontiers in Physiology特邀審稿人。
授課情況：
《生理前沿課》研究生課程（參與）
招生專業：
生理學，神經生物學等
代表性論文和論著：
1. Zhang Z, DiVittorio R. J, Joseph M. A, Correa M. S. The effects of estrogens on neural circuits that control temperature. Endocrinology. 2021; 162(8):bqab087. (Selected for “2020 Thematic Special Issue”).
2. Zhang Z, Park J. W, Ahn I. S., Diamante G., Sivakumar N., Arneson D. V., Yang X., van Veen, J. E.# and Correa, S. M#. Estrogen receptor alpha in the brain mediates tamoxifen-induced changes in physiology in mice. eLife. 2021;10:e63333. (eLife Highlight)
3. Zhang Z, Reis FMCV, He Y, Park JW, DiVittorio JR, Sivakumar N, van Veen JE, Pereira S, Shum M, Anderson S, Nichols I, Paul K, Liesa M, Ajijola OA, Xu Y, Adhikari A, Correa SM. Estrogen-Sensitive Medial Preoptic Area Neurons Coordinate Torpor in Mice. Nature communications, 2020;11:6378
4. Zhang Z, Machado F, Zhao L, Heinen CA, Foppen E, Ackermans MT, Zhou J, Bisschop PH, Boelen A, Fliers E, Kalsbeek A. Administration of thyrotropin-releasing hormone (TRH) in the hypothalamic paraventricular nucleus (PVN) of male rats mimics the metabolic cold defence response, Neuroendocrinology, 2018;107:267–279
5. Zhang Z, Liu J, Veldhuis-Vlug AG, Su Y, Foppen E, van der Eerden BC, Koedam M, Bravenboer N, Kalsbeek A, Boelen A, Fliers E, Bisschop PH. Effects of chronic estrogen administration in the ventromedial nucleus of the hypothalamus (VMH) on fat and bone metabolism in ovariectomized rats, Endocrinology. 2016; 157(12): 4930-4942
6. Zhang Z, Foppen E, Su Y, Bisschop PH, Kalsbeek A, Fliers E, Boelen A. Metabolic effects of chronic T3 administration in the hypothalamic para-ventricular and ventromedial nucleus in male rats, Endocrinology. 2016; 157(10): 4076-4085
7. Zhang Z, Bisschop PH, Foppen E, van Beeren HC, Kalsbeek A, Boelen A, Fliers E. A model for chronic, intrahypothalamic thyroid hormone administration in rats, Journal of Endocrinology 2016; 229(1):37-45 (Cover story)